We present a concept of a nano-electro-mechanical device capable of controlling the position of DNA inside a nanopore with single nucleotide accuracy. The principle of the device operation utilizes the interaction of discrete charges along the backbone of a DNA molecule with the electric field inside the nanopore. We propose an immediate application of our device as a replacement of capillary electrophoresis in DNA sequencing by

By: Stan Polonsky; Gustavo A. Stolovitzky; Stephen Rossnagel

Published in: RC24242 in 2007


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